01605nas a2200229   4500000000100000008004100001260007600042653003500118653001200153653001800165653001800183653002600201653002600227653001200253100002200265245010500287300001000392490000600402520093900408022001401347020001401361       1995                            d  c01/1995bSociedad Española para el Estudio de la Ansiedad y el Estrés10aCNS-immune system interactions10aEmotion10aImmune assays10aImmune system10aNeuroimmunomodulation10aPsychoneuroimmunology10aStress.1 aF. Xavier Borràs00aPsychoneuroimmunology: Psychological stress effects on the immune function in healthy human subjects  a19-330 v13 aPsychoneuroimmunology constitues a new interdisciplinary field that studies interactions between behaviour, brain, and the immune system. After a brief description of the functioning of the immune system and the assays employed for its measurement, the main ways of intercommunication between the central nervous system and the immune system are reviewed. These connections make possible an influence of psychological stress on the immune function. The works made with healthy human subjects experiencing naturalistic stressors of varying intensity and duration show several alterations in inmune competence, such as a minor T-lymphocytes proliferative response, a minor natural killer celll activity, and an elevation of antibody titers against latent herpesvirus. These alterations could increase the vulnerability of the organism toinfectious deseases and cancer, but such clinical implications have no yet been firmly established.  a1134-7937  a2174-0437