01454nas a2200217 4500000000100000008004100001260007600042653002000118653001300138653001100151653001200162653001100174100002200185700001700207245008600224300001000310490000600320520088200326022001401208020001401222 1998 d c01/1998bSociedad Española para el Estudio de la Ansiedad y el Estrés10aGlucocorticoids10aLearning10aMemory10aEmotion10aStress1 aM. Isabel Cordero1 aCarmen Sandi00aStress and cognitive function: The role of glucocorticoids in learning and memory a51-580 v43 aLong-term memory storage is a selective process whereby a decision is made, at the neural level, about the type of information available at a learning experience that should be preserved in memory. The physiological systems involved in the organisms’ response to stress appear as potential modulators of memory formation. In particular, recent studies have indicated that the central actions of corticosteroids -the final products of the hypothalamus-pituitary-adrenal axis activation- are one of the mechanisms implicated in the formation of enduring memories. By acting through specific receptors, these hormones are able to modulate different aspects of neural and behavioural plasticity. In this work, we review the role of glucocorticoids (cortisol or corticosterone, depending on the animal specie) on certain cognitive processes, such as learning and memory formation. a1134-7937 a2174-0437