01805nas a2200289   4500000000100000008004100001260007600042653001200118653001500130653002200145653002300167653001600190100003400206700002300240700002200263700001900285700002100304700002100325700001900346700001900365245012700384300000900511490000700520520096000527022001401487020001401501       2014                            d  c01/2014bSociedad Española para el Estudio de la Ansiedad y el Estrés10aAnxiety10aDepression10aimmune parameters10ameditation program10aMindfulness1 aFrancisco M. Rodríguez-Peña1 aJuan M. Manzaneque1 aFrancisca M. Vera1 aYelba A. Godoy1 aNatalia S. Ramos1 aMaría J. Blanca1 aAna Fernández1 aAlfredo Enguix00aAssessment of immune parameters in anxious and depressive patients after a "mindfulness" meditation program: A pilot study  a1-100 v203 aMindfulness meditation involves concentrating on the present moment in an active and reflexive way. The purpose of this study was to investigate the effects of this form of meditation on immune parameters in a sample of patients with depressive and anxious symptoms. Sixteen patients practiced mindfulness meditation for two months. Several immune parameters, including the total number of leucocytes, lymphocytes, monocytes, neutrophils, eosinophils, basophils, as well as the levels of immunoglobulins (IgA, IgG, IgM) and complement (C3, C4), were measured before and after the program. At post-test, results revealed a significant increase in the concentrations of IgG, IgM, C3 and C4, as well as a decreased monocyte count. Therefore, these findings indicate that mindfulness meditation appears to exert an immunomodulatory action in patients with anxious and depressive symptoms, which suggests interesting psychobiological and clinical implications.  a1134-7937  a2174-0437